Research and development

Publications

In specialist articles, lectures and presentations (for example posters), specialists from Biotest and external scientific and clinical experts report on recent results from research and development.

Here is a list of relevant publications by Biotest.

Clinical immunology

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EASL European Association for the Study of the Liver 22.-26. April 2015, Vienna (Austria). Civacir (Terrault et al.)
PDF, 410.71 kB
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EASL European Association for the Study of the Liver 22.-26. April 2015, Vienna (Austria). Civacir (Tawar et al.)
PDF, 418.76 kB
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EASL European Association for the Study of the Liver 22.-26. April 2015, Vienna (Austria). Zutectra (Zeus)
PDF, 211.81 kB
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Rharbaoui et al.:Therapeutic Potential of Anti-CD4 Mediated Regulatory T-cell Activation
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ACR/ARHP Annual Scientific Meeting; November 14-19, 2014, Boston (USA)
PDF, 391.6 kB
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Helling et al.: A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway. Immunol Cell Biol. 2014 Dec 16. doi: 10.1038/icb.2014.102.
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Terrault et al.: Prevention of Hepatitis C Virus (HCV) Recurrence with Peri-Transplant Hepatitis C Immune Globulin Combined with Pre-Transplant (Pre-LT) Antiviral Therapy (AVT)
PDF, 214.92 kB
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ACR/ARHP Annual Scientific Meeting, November 9.-14.2012, Washington, D.C., (USA)
PDF, 372.84 kB
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Haematology

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ASH 2014 American Society of Hematology (06.12.2014 – 09.12.2014, San Francisco)
PDF, 398.98 kB
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World ADC Weltkongress Antibody Drug Conjugates (26.10.2014 – 29.10.2014, San Diego)
PDF, 834.64 kB
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ASH 2013 American Society of Hematology (06.12.2013 - 10.12.2013, New Orleans)
PDF, 41.61 kB
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ASH 2012 American Society of Hematology, 8. - 11. Dez. 2012, Atlanta (USA)
PDF, 387.58 kB
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Ikeda et al.: The monoclonal antibody nBT062 conjugated to cytotoxic Maytansinoids has selective cytotoxicity against CD138-positive multiple myeloma cells in vitro and in vivo.Clin Cancer Res. 2009, Jun 15;15(12):4028-37
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Tassone et al.: Cytotoxic activity of the maytansinoid immunoconjugate B-B4-DM1 against CD138+ multiple myeloma cells. Blood. 2004 Dec 1;104(12):3688-96
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Intensive care medicine

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Schmiedl et al.: Safety of the IgM enriched immunoglobulin concentrate BT086 in healthy volunteers – results of a dose-escalating single dose phase I study. Br J Clin Pharmacol 2011, 72:1-46. Abstract 40
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Schmiedl et al.: Evaluation of pharmacokinetics and safety of the IgM enriched immunoglobulin concentrate BT086 in healthy volunteers - results of a multiple dose phase I study. Br J Clin Pharmacol 2011, 72:1-46. Abstract 43
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Welte et al.: Concept for a study design in patients with severe community-acquired pneumonia: A randomised controlled trial with a novel IGM-enriched immunoglobulin preparation – The CIGMA study. Respiratory Medicine , Volume 109 , Issue 6 , 758 - 767
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